THE SHORT VERSION
Sicily to Rome at a glance.
- From
- Sicily Isola di Sicilia
- To
- Rome Roma
- Straight line
- 511 km
- Return route
- Rome to Sicily →
Ready to travel from Sicily to Rome?
Check live availability, fares and departure times with 12Go.
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Sicily
Boarding points depend on the operator: some use the local bus station, others collect from their office or your hotel. Your ticket shows the exact place and check-in time.
Arriving in Rome
Tiburtina is on metro line B, a few stops from Termini.
- Roma Tiburtina coach terminal
Next to Tiburtina railway station (metro line B). FlixBus and most long-distance coaches. - Termini and airport stops
Airport shuttles and some services use Termini station and the airports.

Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
- Allow time for Rome traffic when connecting with flights.
KEEP GOING
From Rome, the road continues.
This trip includes a boat crossing. For ferry routes and timetables, see our sister site FerryConnect.
Other ways to reach Rome
More buses from Sicily
GOOD QUESTIONS
Before you take your seat.
How long does the bus from Sicily to Rome take?+
Journey times depend on the service and any boat connection. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Sicily?+
It depends on the operator: some use the local bus station, others collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Rome to Sicily?+
Yes, 12Go also lists services in the opposite direction. See our Rome to Sicily guide.
Where does the bus from Sicily arrive in Rome?+
It depends on the operator. In Rome, services use Roma Tiburtina coach terminal, Termini and airport stops. Tiburtina is on metro line B, a few stops from Termini.
How do I get from the bus stop to the centre of Rome?+
Tiburtina is on metro line B, a few stops from Termini.
What kind of bus runs from Sicily to Rome?+
Tickets to Rome usually combine a bus or van with a boat. The vehicle type, seat style and boat connection are shown for each departure on 12Go.
Can I book the Sicily to Rome bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Rome by bus?+
Direct buses from Rome include Naples, Florence, Venice, Milan, Nice and more. See all connections on our Rome bus page.
Does the trip to Rome include a ferry?+
Yes, Rome is an island, so the journey includes a boat crossing. Check whether your ticket covers the boat and the transfer from the pier, and allow for weather delays.
Still deciding? Check today's departures, then book your seat.
Book Sicily → Rome on 12GoFOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Station information reviewed 2026-10-09. Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Sicily to Rome bus route listing ↗Wikivoyage: Rome (Get in) ↗How BusConnects uses sources →