THE SHORT VERSION
Rome to Madrid at a glance.
Ready to travel from Rome to Madrid?
Check live availability, fares and departure times with 12Go.
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Rome
Rome is Italy's biggest coach destination, with domestic routes and overnight connections to France, Switzerland and Germany. Most long-distance buses use the coach terminal next to Tiburtina station.
- Roma Tiburtina coach terminal
Next to Tiburtina railway station (metro line B). FlixBus and most long-distance coaches. - Termini and airport stops
Airport shuttles and some services use Termini station and the airports.
Arriving in Madrid
Both stations are on the metro (Méndez Álvaro on line 6; Avenida de América on lines 4, 6, 7 and 9).
- Estación Sur de Autobuses
Méndez Álvaro, 1 km south-east of Atocha. International routes and routes to the south and west, including Lisbon. - Avenida de América
2 km north-east of the centre. Routes to the north, such as Barcelona and Bilbao.
Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
- Some buses also call at Madrid-Barajas airport.
KEEP GOING
From Madrid, the road continues.
Other ways to reach Madrid
More buses from Rome
GOOD QUESTIONS
Before you take your seat.
How far is Rome from Madrid by road?+
About 1948 km by road (1363 km in a straight line). Distance is an OpenStreetMap routing estimate, not an operator figure.
How long does the bus from Rome to Madrid take?+
We don't publish timetables. As a guide, the drive takes roughly 21 h by car without stops; bus journeys are usually longer. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Rome?+
It depends on the operator. Main options in Rome include Roma Tiburtina coach terminal, Termini and airport stops, and many tourist companies collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Madrid to Rome?+
12Go's public route list doesn't include Madrid to Rome as a direct route. You may need to change in another town.
Where does the bus from Rome arrive in Madrid?+
It depends on the operator. In Madrid, services use Estación Sur de Autobuses, Avenida de América. Both stations are on the metro (Méndez Álvaro on line 6; Avenida de América on lines 4, 6, 7 and 9).
How do I get from the bus stop to the centre of Madrid?+
Both stations are on the metro (Méndez Álvaro on line 6; Avenida de América on lines 4, 6, 7 and 9).
What kind of bus runs from Rome to Madrid?+
It varies by operator and departure. Routes in this region are served by a mix of sleeper buses, seated coaches and smaller limousine vans. Check the vehicle type, seat layout and luggage allowance for your departure on 12Go before you book.
Can I book the Rome to Madrid bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Madrid by bus?+
Direct buses from Madrid include Valencia, Seville, Porto, Barcelona, Lisbon and more. See all connections on our Madrid bus page.
Do I need my passport on the bus from Rome to Madrid?+
Italy and Spain are both in the Schengen area, so there are usually no routine border checks. Carry your passport or national ID card anyway: spot checks happen and operators may ask for ID.
Still deciding? Check today's departures, then book your seat.
Book Rome → Madrid on 12GoFOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Station information reviewed 2026-10-09. Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Rome to Madrid bus route listing ↗Wikivoyage: Rome (Get in) ↗Wikivoyage: Madrid (Get in) ↗How BusConnects uses sources →