THE SHORT VERSION
Prague to Madrid at a glance.
Ready to travel from Prague to Madrid?
Check live availability, fares and departure times with 12Go.
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Prague
Prague is a major coach hub for central Europe, with frequent buses to Vienna, Munich, Berlin, Budapest and Kraków. The main coach station is Florenc, east of the centre.
- ÚAN Praha-Florenc
East of the centre, at Florenc metro (lines B and C). Most long-distance coaches. - Na Knížecí
By Anděl metro (line B). Some domestic and international services.
Arriving in Madrid
Both stations are on the metro (Méndez Álvaro on line 6; Avenida de América on lines 4, 6, 7 and 9).
- Estación Sur de Autobuses
Méndez Álvaro, 1 km south-east of Atocha. International routes and routes to the south and west, including Lisbon. - Avenida de América
2 km north-east of the centre. Routes to the north, such as Barcelona and Bilbao.
Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
- Some buses also call at Madrid-Barajas airport.
KEEP GOING
From Madrid, the road continues.
Other ways to reach Madrid
More buses from Prague
GOOD QUESTIONS
Before you take your seat.
How far is Prague from Madrid by road?+
About 2241 km by road (1772 km in a straight line). Distance is an OpenStreetMap routing estimate, not an operator figure.
How long does the bus from Prague to Madrid take?+
We don't publish timetables. As a guide, the drive takes roughly 23 h by car without stops; bus journeys are usually longer. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Prague?+
It depends on the operator. Main options in Prague include ÚAN Praha-Florenc, Na Knížecí, and many tourist companies collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Madrid to Prague?+
12Go's public route list doesn't include Madrid to Prague as a direct route. You may need to change in another town.
Where does the bus from Prague arrive in Madrid?+
It depends on the operator. In Madrid, services use Estación Sur de Autobuses, Avenida de América. Both stations are on the metro (Méndez Álvaro on line 6; Avenida de América on lines 4, 6, 7 and 9).
How do I get from the bus stop to the centre of Madrid?+
Both stations are on the metro (Méndez Álvaro on line 6; Avenida de América on lines 4, 6, 7 and 9).
What kind of bus runs from Prague to Madrid?+
It varies by operator and departure. Routes in this region are served by a mix of sleeper buses, seated coaches and smaller limousine vans. Check the vehicle type, seat layout and luggage allowance for your departure on 12Go before you book.
Can I book the Prague to Madrid bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Madrid by bus?+
Direct buses from Madrid include Valencia, Seville, Porto, Barcelona, Lisbon and more. See all connections on our Madrid bus page.
Do I need my passport on the bus from Prague to Madrid?+
Czechia and Spain are both in the Schengen area, so there are usually no routine border checks. Carry your passport or national ID card anyway: spot checks happen and operators may ask for ID.
Still deciding? Check today's departures, then book your seat.
Book Prague → Madrid on 12GoFOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Station information reviewed 2026-10-09. Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Prague to Madrid bus route listing ↗Wikivoyage: Prague (Get in) ↗Wikivoyage: Madrid (Get in) ↗How BusConnects uses sources →