THE SHORT VERSION
Phitsanulok to Khon Kaen at a glance.
- From
- Phitsanulok พิษณุโลก
- To
- Khon Kaen ขอนแก่น
- Road distance
- About 321 km
- Straight line
- 276 km
- Car time, no stops
- ~4 h 15 min buses take longer
- Return route
- Khon Kaen to Phitsanulok →
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Phitsanulok
Phitsanulok is a city in lower northern Thailand on the main north–south rail line, and a gateway to Sukhothai. Buses run to Bangkok, Chiang Mai, Sukhothai and the north-east.
- Phitsanulok bus terminals
Two terminals; long-distance services use the one outside the centre.
Arriving in Khon Kaen
Use a tuk-tuk, songthaew or ride-hail to the centre.
- Khon Kaen bus terminals
Several terminals; long-distance services use the newer terminal outside the centre.

Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
- Check which terminal your bus uses.
KEEP GOING
From Khon Kaen, the road continues.
Other ways to reach Khon Kaen
More buses from Phitsanulok
USEFUL FOR THIS TRIP
Sort the small things before you go.
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GOOD QUESTIONS
Before you take your seat.
How far is Phitsanulok from Khon Kaen by road?+
About 321 km by road (276 km in a straight line). Distance is an OpenStreetMap routing estimate, not an operator figure.
How long does the bus from Phitsanulok to Khon Kaen take?+
We don't publish timetables. As a guide, the drive takes roughly 4 h 15 min by car without stops; bus journeys are usually longer. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Phitsanulok?+
It depends on the operator. Main options in Phitsanulok include Phitsanulok bus terminals, and many tourist companies collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Khon Kaen to Phitsanulok?+
Yes, 12Go also lists services in the opposite direction. See our Khon Kaen to Phitsanulok guide.
Where does the bus from Phitsanulok arrive in Khon Kaen?+
It depends on the operator. In Khon Kaen, services use Khon Kaen bus terminals. Use a tuk-tuk, songthaew or ride-hail to the centre.
How do I get from the bus stop to the centre of Khon Kaen?+
Use a tuk-tuk, songthaew or ride-hail to the centre.
What kind of bus runs from Phitsanulok to Khon Kaen?+
It varies by operator and departure. Routes in this region are served by a mix of sleeper buses, seated coaches and smaller limousine vans. Check the vehicle type, seat layout and luggage allowance for your departure on 12Go before you book.
Can I book the Phitsanulok to Khon Kaen bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Khon Kaen by bus?+
Direct buses from Khon Kaen include Udon Thani, Nong Khai, Nakhon Ratchasima (Korat), Ubon Ratchathani, Sukhothai and more. See all connections on our Khon Kaen bus page.
FOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Station information reviewed 2026-10-09. Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Phitsanulok to Khon Kaen bus route listing ↗Wikivoyage: Phitsanulok (Get in) ↗Wikivoyage: Khon Kaen (Get in) ↗How BusConnects uses sources →